• BMF 96 - 13C-labelled internal standards for toxicology

    BMF 96 - 13C-labelled internal standards for toxicology

    Quantitation of an analyte is usually accomplished by measuring the response obtained relative to an internal standard (IS). These are used to compensate for loss of analyte during sample preparation and for variation in mass spectrometric analysis (i.e. ionization efficiency and subtle variations in MS analysis). The assumption is that IS losses will be similar to losses of analyte. If a known quantity of IS is added to the unknown sample prior to any manipulations, the ratio of IS to analyte remains constant, because the same fraction of each is lost in any operation.


    Find out more about the properties on an ideal IS, and the relative advantages and disadvantages of deuterated vs 13C labelled variants in our latest newsletter; BMF 96

  • BMF 95 - Coronavirus (COVID-19)

    BMF 95 - Coronavirus (COVID-19)

    Coronavirus disease 2019 (COVID-19 or SARS-CoV-2) is a virus that first appeared in Wuhan, China in late 2019. COVID-19 is a virus that is likely to have zoonotic origins much like other coronaviruses; SARS (SARS-CoV) and MERS. This disease is highly contagious and is now classified as a pandemic. Although most people infected are asymptomatic, have mild or varied symptoms, severe cases include difficulty breathing and require hospitalisation. The vulnerable population include people over 60 and those with a weakened immune system or pre-existing health conditions. People with higher chances of complications include smokers, those with diabetes, cardiovascular disease, chronic respiratory disease, and cancer. Since there are still many unknowns, researching this disease is paramount amongst the scientific community. Currently, there are no vaccines or treatments for COVID-19, but some clinical trials aim to find drugs already available to help aid in treatment of the disease.


    Chiron now offer a range of reference materials for the proposed COVID-19 therapeutics, to support hospital and research laboratories in their vital search for a cure.

    View our offering here

  • BMF 92 - Antibiotics

    BMF 92 - Antibiotics

    Antibiotics are medicines used to treat infections caused by bacteria. People at a high risk may also be given antibiotics to prevent bacterial infections, known as antibiotic prophylaxis. Antibiotics work by killing bacteria i.e. by destroying the cell wall (bactericidal), or preventing them from reproducing and spreading (bacteriostatic). Mild bacterial infections usually get better on their own without using antibiotics. Instead antibiotics should be reserved to treat bacterial infections that are unlikely to resolve on their own, may have a prolonged duration, or lead to serious complications if left untreated. They are also prescribed when an infection may pose a risk to others. When prescribed, antibiotics are effective in easing symptoms and speeding up recovery. In some instances they are lifesaving! Antibiotics don’t work against viral infections such as colds and flu.


    Click here to find out more.

  • EMCDDA list

    EMCDDA list

    Here is the new list of EMCDDA products


    EMCDDA list download

  • BMF 86 - Carfentanil

    BMF 86 - Carfentanil

    Carfentanyl is an ultra-potent synthetic opioid. It is the most powerful opioid commercially available, being 10,000 times stronger than morphine and 100 times more potent than fentanyl. It can be fatal in the low to sub milligram range. Carfentanyl is not approved for human use, but is instead intended for use in veterinary practice, to rapidly incapacitate large animals. 

    Read more about Carfentanil and what Chiron can offer here.

  • BMF 85 - Biogenic Amines

    BMF 85 - Biogenic Amines

    Phaeochromocytoma (PCC) is a rare tumour in the adrenal glands, affecting less than 1 person per 2,000.

    The tumour causes excess secretion of catecholamine’s resulting in hypertension, but can also lead to diabetes-like symptoms.

    Laboratory diagnosis includes measurement of urine catecholamine’s or urine and plasma metanephrines.

    Chiron now offer native and labelled standards as well as standard mixes for these diagnostic markers.

    Find out more about PCC and available standards: biogenic amine newsletter.

  • BMF 84 - Antipsychotics

    BMF 84 - Antipsychotics

    According to the World Health Organization (WHO), schizophrenia affects 21 million people worldwide.

    Schizophrenia is treatable with antipsychotics, enabling sufferers to lead a productive life and be integrated in society.

    Antipsychotics are commonly detected or monitored in toxicology case work.

    Chiron offer a wide range of antipsychotic reference materials and associated internal standards to aid laboratory analysis.


    Click here to find out more.

  • BMF 83- Antidepressants

    BMF 83- Antidepressants

    Depression is a common psychiatric disorder impacting millions of people worldwide. It is caused by an imbalance of chemicals in the brain, namely serotonin and noradrenaline. Everyone experiences highs and lows, but depression is characterised by persistent sadness for weeks or months. With depression there is lasting feeling of hopelessness, often accompanied by anxiety. Sufferers lose interest in things that they previously enjoyed, and experience bouts of tearfulness. Rational thinking and decision making are impacted. Physical manifestations include tiredness, insomnia, loss of appetite and sex drive, aches and pains. At its worst depression can cause the sufferer to feel suicidal.


    Chiron offer a wide range of antidepressant reference materials and associated internal standards


    Download our newsletter on Antidepressants here.

  • Kura Biotec

    Kura Biotec

    Kura Biotec-The β-glucuronidase Experts!


    Inspired by Nature, Moved by Science. What started as a way of sustainably recycling byproducts from a family owned abalone-farm took a five-year R&D ride to give birth to the purest and fastest known beta-glucuronidase.


    Download the flyer here.

  • BMF 77- Alcohol Biomarkers

    BMF 77- Alcohol Biomarkers

    Self-reporting of alcohol consumption is objective and inherently unreliable.  This has led to an intensive search for a reliable marker of chronic, excessive drinking. The detection of ethanol in biological specimens indicates recent alcohol consumption or exposure but the detection window is very short. Alcohol biomarkers can be used to extend the time window for detection and can persist long after complete elimination of ethanol. In this way they are useful relapse or abstinence markers. 


    Download the BMF newsletter here.

  • BMF 78-Methylphenidate Related New Psychoactive Substances

    BMF 78-Methylphenidate Related New Psychoactive Substances

    Methylphenidate (Ritalin) is a prescription only medication used for the treatment of attention deficit hyperactivity disorder (ADHD). It also has an unlicensed application in the treatment of narcolepsy. Due to its stimulant effects it is under International control, appearing in Schedule II of the Convention on Psychotropic Substances of 1971 (Green list). The recommended dosage for children between 6 and 18 years is a maximum of 60mg daily in 2-3 divided daily doses. Tablets are available as 5, 10 or 20mg. Serum therapeutic concentrations of methylphenidate are between 5-60ng/mL and toxicity has been observed with concentrations exceeding 500ng/mL.


    Download the BMF newsletter here!


  • BMF 75-Benzodiazepines

    BMF 75-Benzodiazepines

    Benzodiazepines are a common class of prescription medication. There are over fifty different types of benzodiazepines worldwide. They are used therapeutically for a number of applications, including control of epilepsy, reducing anxiety, as premedication adjuncts to anaesthesia, to treat insomnia, and for alcohol withdrawal. Benzodiazepines are also a frequently abused class of drugs. Abuse can be broadly divided into 3 main categories: 1) Over prescribing for legitimate indications, 2) recreational abuse, 3) drug facilitated crime.

    Benzodiazepines have a high addition potential and over prescription can lead to dependency. Better recognition of this has resulted in a gradual reduction in the number of benzodiazepine prescriptions issued. They are one of the most common prescription drugs abused recreationally. Benzodiazepines are abused for the buzz or rush that follows rapid injection or otherwise for their alcohol like effects. Polydrug abuse involving benzodiazepines is common. They are used to enhance the effects of other CNS depressant drugs, alleviate withdrawal effects or combat effects of stimulants, i.e. to enable sleep and to reduce stress, anxiety and depression following their use. The hypnotic effect of benzodiazepines also makes them potential candidates for drug facilitated crimes such as date rape, robbery or neglect. 

    Download the BMF newsletter here!

  • BMF 44 - Spice

    BMF 44 - Spice

    Spice (also known as K2) is a brand name for a mixture of herbs that has been sold in “smartshops” in Europe since around 2002. The term is often used to describe synthetic cannabinoids that act as agonists at the cannabis receptors in the brain, the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor. These compounds have similar effects as THC in humans and animals. THC is one of over 400 cannabinols present in cannabis plants and is responsible for the 'high' associated with smoking cannabis. Many countries have already added these compounds to their list of controlled substances, and more are likely to follow soon. This has led to an increasing interest from forensic, clinical and toxicology labs all over the world.


    Chiron proudly presents a wide range of spice-compounds. We are continuously expanding our selection of these products, if you are looking for some that are not listed here, please contact us. We may still be able to offer.

    Download the BMF newsletter here!

  • BMF 46 - Amphetamines and designer drugs

    BMF 46 - Amphetamines and designer drugs

    The term designer drug refers to chemicals that are synthesised with the intention to bypass drug legislations. This is usually done by modifying the molecular structure without loosing the subjective effects one gets from the original drug. In the last decade there has been a massive increase in the amount of designer drugs sold via the internet.


    Many of the chemicals fall under the various drug analogue legislations in certain countries, but most countries have no general analogue act or equivalent legislation. Novel compounds often fall outside of the law after only minor structural modifications.

    The most important groups of designer drugs are amphetamine derivates like MDMA and other Ecstasy compounds, phenylcyclidin, fentanyl derivates, petidin derivates and designer cannabinoids, also known as Spice-compounds (See our BMF 44-Spice).

    Also see our New Psychoactive Substance 2014 product catalogue

    Download the BMF newsletter here!

  • BMF 47 Allergens European standard CEN/TC 347/WG 4N 19

    BMF 47 Allergens European standard CEN/TC 347/WG 4N 19

    24 Suspected allergens in analytical purity.

    Safe and accurate analysis of priority suspected allergens has been hampered by the lack of pure and reliable standards. Many of the known allergens have only been available as mixtures of isomers or impure compounds, and purities stated by various fine chemical suppliers has proven to be unreliable for most of these substances. Chiron has purified each individual allergen in order to obtain a reliable standard mixture of the 24 suspected compounds as suggested in the new
    CEN/TC347/WG 4N 19 method, altogether 26 isomers.


    Chiron AS offers highly purified substances for allergen analysis and toxicological studies, as well as a convenient all-in-one mixture.

    Download the BMF newsletter here!

  • BMF 62 - SPICE metabolites

    BMF 62 - SPICE metabolites

    Spice - also known as K2 - are smokable herbal products wich are spiked with compounds like JWH-018. This drugs act as agonists at the cannabis receptors in the brain, the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor. They show similar psychological effects like D9-tetrahydrocannabinol (D9-THC). The most common compounds are JWH-018, JWH-073, and JWH-250. However, several others are also in use. Many countries have already added these compounds to their list of controlled substances, and more are likely to follow soon. This has led to an increasing interest from forensic, clinical and toxicology labs all over the world.


    Chiron proudly presents a wide range of spice-metabolites and their internal standards. We are continuously expanding our selection of these products, if you are looking for some that are not listed here, please contact us. We may still be able to offer.

    Download the BMF newsletter here!