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BMF 55 - Nitrosoamines
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Chiron has built up a strong track record of supplying new reference standards during the past 28 years of operation. We are now proud to announce our offer of nitrosoamine reference standards.
The basis of a good analytical method is the availability of appropriate standards of defined purity and concentration.
Our mission is to market highly purified calibrates in crystalline as well as standardized solutions for chemical analysis, including internal standards. Your benefits using our standards include:
• Fast turnover time due to excellent service
• Guaranteed high and consistent quality
• Sufficient capacity to serve the market, and bulk quantities available on request
• Custom solutions and custom synthesis on request.
• We continuously develop new and innovative products.
Nitrosoamines are a class of chemical compounds that have received much attention since 1956, when two British scientists, John Barnes and Peter Magee, reported that dimethylnitrosoamine produced liver tumors in rats. Nitrosoamines are formed by reactions of nitrits and secondary amines (e.g. in proteins) under acidic conditions like gastric milieus. Human beings ingest nitrits from food, esp. fried or grilled meat and vegetables. Disposal of tabacco products also causes a high intake of nitrosoamines (mainly N-Nitrosonornicotine). Also chemical industry is responsible for exposure of nitrosoamines e.g. the rubber manufacturing and metal industry.
Chiron provides several native nitrosamines and internal standards (according to EPA 621)
Native nitrosoamines for EPA 621
Product No Name and Description, Concentration, Solvent and Quantity
9004.2-2K-DC, N-Nitrosodimethylamine, NDMA, 2000ìg/mL, DCM, 1mL
9004.2-100MG, N-Nitrosodimethylamine, NDMA, neat, 100 mg
9005.3-2K-DC, N-Nitrosomethylethylamine, NMEA, 2000ìg/mL, DCM, 1mL
9005.3-100MG, N-Nitrosomethylethylamine, NMEA, neat, 100 mg
9006.4-2K-DC, N-Nitrosodiethylamine, NDEA, 2000ìg/mL, DCM, 1mL
9006.4-100MG, N-Nitrosodiethylamine, NDEA, neat, 100 mg
9007.6-2K-DC, N-Nitrosodi-n-propylamine, NDPA, 2000ìg/mL, DCM, 1mL
9007.6-100MG, N-Nitrosodi-n-propylamine, NDPA, neat, 100 mg
9008.8-2K-DC, N-Nitrosodi-n-butylamine, NDBA, 2000ìg/mL, DCM, 1mL
9009.4-2K-DC, N-Nitrosopyrolidine, NPYR, 2000ìg/mL, DCM, 1mL
9009.4-100MG, N-Nitrosopyrolidine, NPYR, neat, 100 mg
9010.5-2K-DC, N-Nitrosopiperidine, NPIP, 2000ìg/mL, DCM, 1mL
9010.5-100MG, N-Nitrosopiperidine, NPIP, neat, 100 mg
Internal standards for EPA 621
Product No Name and Description, Concentration, Solvent and Quantity
9011.2-K-DC, N-Nitrosodimethylamine-d6, NDMA-d6, 1000μg/mL, DCM, 1mL
9012.3-K-DC, N-Nitrosomethylethylamine-d3, NMEA-d3, 1000μg/mL, DCM, 1mL
9013.4-K-DC, N-Nitrosodiethylamine-d10, NDEA-d10, 1000μg/mL, DCM, 1mL
9014.6-K-DC, N-Nitrosodi-n-propylamine-d14, NDPA-d14, 1000μg/mL, DCM, 1mL
9015.8-K-DC, N-Nitrosodi-n-butylamine-d18, NDBA-d18, 1000μg/mL, DCM, 1mL
9016.4-K-DC, N-Nitrosopyrolidine-d8, NPYR-d8, 1000μg/mL, DCM, 1mL
9017.5-K-DC, N-Nitrosopiperidine-d10, NPIP-d10, 1000μg/mL, DCM, 1mL
Other nitrosoamines
Product No Name and Description, Concentration, Solvent and Quantity
1703.10-K-AN, 4-(N-Methyl-N-nitrosoamino)-1-(3-pyridyl)-1-butanone, 1000μg/mL, acetonitrile, 1mL
2743.12-K-IP, N-Nitroso-di-n-hexylamine, 1000μg/mL, isopropanol, 1mL
9688.8-K-AN, N-Nitroso-N-ethylaniline, 1000μg/mL, acetonitrile, 1mL
8926.2-K-AN, N-Nitroso-N-methylurea NMU, 1000μg/mL, acetonitrile, 1mL
8986.4-K-AN, N-Nitrosopiperazine, 1000μg/mL, acetonitrile, 1mL
8986.4-100MG, N-Nitrosopiperazine, neat, 100mg
9018.7-K-AN, N-Nitrosomethylphenylamine, 1000μg/mL, acetonitrile, 1mL
9019.4-K-AN, 1,4-Dinitrosopiperazine, 1000μg/mL, acetonitrile, 1mL
9019.4-100MG, 1,4-Dinitrosopiperazine, neat, 100mg
9326.4-K-AN, N-Nitrosomorpholine, 1000μg/mL, acetonitrile, 1mL
9326.4-100MG, N-Nitrosomorpholine, neat, 100mg
9328.12-K-AN, N-Nitrosodiphenylamine, Ndiphen, 1000μg/mL, acetonitrile, 1mL
9666.4-K-AN, N-Nitrosodiethanolamine, 1000μg/mL, acetonitrile 1mL
9666.4-100MG, N-Nitrosodiethanolamine, neat, 100mg
Other nitrosoamine internal standards
Product No Name and Description, Concentration, Solvent and Quantity
9327.4-100-AN, 4-Nitrosomorpholine-d8 100μg/mL, acetonitrile, 1mL
9022.4-100-AN, 1,4-Dinitrosopiperazine-d8, 100μg/mL, acetonitrile, 1mL
1707.10-K-AN, 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone-d4, 1000μg/mL, acetonitrile, 1mL
Nicotine nitrosoamines including internal standards
Product No Name and Description, Concentration, Solvent and Quantity
1702.9-K-AN, N-Nitrosonornicotine, 1000μg/mL, acetonitrile, 1mL
1706.9-K-AN, DL-N-Nitrosonornicotine-d4, 1000μg/mL, acetonitrile, 1mL
1706.9-K-2AN, DL-N-Nitrosonornicotine-d4, 1000μg/mL, acetonitrile, 2mL
1705.10-K-AN, (RS)-N-Nitrosoanatabine, 1000μg/mL, acetonitrile, 1mL
1704.10-K-AN, (RS)-N-Nitrosoanabasine, 1000μg/mL, acetonitrile, 1mL
We are steadily updating our product portfolio to reflect the market for reference standards and we are proud to present our new developed nitrosoamine:
Product No Name and Description, Concentration, Solvent and Quantity
9329.14-K-AN, N-Nitrosodibenzylamine, 1000μg/mL, acetonitrile, 1mL
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